Acetyl and benzoyl groups were not affected in the ring closure reactions. The title compounds 5-O-acetyl-1,2-anhydro-3-O-benzyl-alpha -D-ribofuranose and 5-O-acetyl-1,2-anhydro-3-O-benzyl-beta -D-lyxofuranose, and 6-O-acetyl-1,2-auhydro-3,4-di-O-benzyl-alpha -D-glucopyranose and 6-O-acetyl-1,2-anhydro-3,4-diO-benzyl-beta -D-taloypranose, and 5-O-acetyl-1,2-anhydro-3,6-di-O-benzyl-beta -D-mannofuranose and 1,2-anhydro-5,6-di-O-benzoyl-3-O-benzyl-beta -D-mannofuranose have each been synthesized from the corresponding 2-O-tosylate and 1-free hydroxyl inter-mediates by base-initiated intramolecular S(N)2 ring closure in almost quantitative yields. cAMP and cGMP, formed from ATP and GTP, serve as secondary messengers in some signalling pathways. Phosphorylated derivatives of ribose such as ATP and NADH play central roles in metabolism. It is related to deoxyribose, which is found in DNA. The ribose β-D-ribofuranose forms part of the backbone of RNA. Moreover, ribose is found to be associated with ribose-5-phosphate isomerase deficiency. Ribose is also involved in few metabolic disorders, which include glucose-6-phosphate dehydrogenase deficiency, ribose-5-phosphate isomerase deficiency, and transaldolase deficiency. In humans, ribose is involved in the pentose phosphate pathway. Ribose exists in all living species, ranging from bacteria to humans. Ribose can be found primarily in most biofluids, including urine, cerebrospinal fluid (CSF), saliva, and feces, as well as throughout most human tissues. Ribose can be found in a number of food items such as lemon verbena, devilfish, watercress, and chicory roots, which makes ribose a potential biomarker for the consumption of these food products. Ribose is very soluble (in water) and a very weakly acidic compound (based on its pKa). Pentoses are monosaccharides in which the carbohydrate moiety contains five carbon atoms. Ribose, also known as D-ribose or alpha-delta-ribose-5, is a member of the class of compounds known as pentoses. Back to Compounds Showing Compound β-D-ribofuranose (FDB031292) Record Information

Alpha d ribofuranose